Effect of Testosterone on Intracavernous Pressure Elicited with 1 Electrical Stimulation of the Medial Preoptic Area and Cavernous 2 Nerve in Male Rats
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چکیده
Correspondence and Galley proofs: 14 Shin-ichi Hisasue, M.D. 15 Department of Urology, Sapporo Medical University School of 16 Medicine, S1-W16, Chuo-ku, Sapporo, Hokkaido, Japan 060-8543 17 Tel: 81-(0)11-611-2111 ext. 3472, Fax: 81-(0)11-612-2709 18 E-mail: [email protected] 19 20 Financial support: This work was supported in part by 21 grants-in-aid for scientific research (12671547 and 16591605) 22 from the Japanese Society for the Promotion of Science. 23
منابع مشابه
Effect of testosterone on intracavernous pressure elicited with electrical stimulation of the medial preoptic area and cavernous nerve in male rats.
We studied the effects of castration and testosterone (T) replacement on intracavernous pressure (ICP) elicited with electrical stimulation of the medial preoptic area (MPOA) and cavernous nerve (CN) in male rats. We measured the ICP during electrical stimulation of the MPOA and CN in castrated male rats with and without testosterone replacement. The experimental group consisted of 20-week-old ...
متن کاملDifferential ICP responses elicited by electrical stimulation of medial preoptic area
Sato, Yoshikazu, and George J. Christ. Differential ICP responses elicited by electrical stimulation of medial preoptic area. Am. J. Physiol. Heart Circ. Physiol. 278: H964–H970, 2000.—Recent findings indicate a complex role for the medial preoptic area (MPOA) in modulating penile erection. To further investigate this important area we measured changes in intracavernous pressure (ICP) elicited ...
متن کاملErectile response to hypothalamic stimulation in rats: role of peripheral nerves.
The role of peripheral parasympathetic and sympathetic pathways was explored in erectile responses elicited by hypothalamic medial preoptic area (MPOA) stimulation in adult male anesthetized rats. Under control conditions, MPOA stimulation reliably elicited erectile responses evidenced by an increase of the intracavernous pressure-to-blood pressure ratio. The erectile response was abolished by ...
متن کاملCentral modulation of the NO/cGMP pathway affects the MPOA-induced intracavernous pressure response
Sato, Yoshikazu, Weixin Zhao, and George J. Christ. Central modulation of the NO/cGMP pathway affects the MPOA-induced intracavernous pressure response. Am J Physiol Regulatory Integrative Comp Physiol 281: R269–R278, 2001.—Alterations in the nitric oxide (NO)/ cGMP levels in hypothalamic nuclei, including the medial preoptic area (MPOA), regulate critical aspects of sexual behavior and penile ...
متن کاملCentral modulation of the NO/cGMP pathway affects the MPOA-induced intracavernous pressure response.
Alterations in the nitric oxide (NO)/cGMP levels in hypothalamic nuclei, including the medial preoptic area (MPOA), regulate critical aspects of sexual behavior and penile reflexes. However, the effects of altered central nervous system (CNS) NO/cGMP levels at the end organ level, that is, on the magnitude/quality of the erection so achieved [intracavernous pressure (ICP) response], has yet to ...
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